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YC Lab Publications

Chemical & Biological Engineering | HKUST
2022 | 2021 | 2020  |  2019  |  2018  |  2017  |  2016  |  2015  |  2014  |  2013  |  2012  |  2011  | 2010 | 
​ 2009  |  2008  |  2006  |  2005  |  BEFORE 2005

2022

 
  • Liu J., Zhorabek F., Dai X., Huang J. and Chau Y. (2022). Minimalist design of intrinsically disordered protein-mimicking scaffold for artificial membraneless organelle. ACS Cent. Sci.
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2021

 
  • Feng, R., Ni, R. and Chau, Y. (2021), Altered Peptide Self-Assembly and Co-Assembly with DNA by Modification of Aromatic Residues. ChemMedChem. https://doi.org/10.1002/cmdc.202100440
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  • Chung, J. T., Lau, C. M. L., Chau, Y. (2021). The effect of polysaccharide-based hydrogel on the response of antigen presenting cell line to immunomodulators. Biomater. Sci. https://doi.org/10.1039/D1BM00854D
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  • Chung, C. H. Y., Lau, C. M. L., Sin, D. T., Chung, J. T., Zhang, Y., Chau, Y., Yao, S. (2021). Droplet-Based Microfluidic Synthesis of Hydrogel Microparticles via Click Chemistry-Based Cross-Linking for the Controlled Release of Proteins. ACS Applied Bio Materials. https://doi.org/10.1021/acsabm.1c00509
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  • Yu, Y., Chow, D. W. Y., Lau, C. M. L., Zhou, G., Back, W., Xu, J., … Chau, Y. (2021). A bioinspired synthetic soft hydrogel for the treatment of dry eye. Bioengineering & Translational Medicine, (February), 1–11. https://doi.org/10.1002/btm2.10227
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  • Lau, C. M. L., Jahanmir, G., Yu, Y., & Chau, Y. (2021). Controllable multi-phase protein release from in-situ hydrolyzable hydrogel. Journal of Controlled Release. ​https://authors.elsevier.com/c/1d5CfcI2~wUBO 
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2020

  • HUANG, X., Chau, Y. (2020). Enhanced delivery of siRNA to retinal ganglion cells by intravitreal lipid nanoparticles of positive charge, Molecular Pharmaceutics, Accepted
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  • Jahanmir, G., Lau, C. M. L., Abdekhodaie, M. J., & Chau, Y. (2020). A dual-diffusivity stochastic model for macromolecule release from hydrogel. ACS Applied Bio Materials 3(7), 4208–4219.
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  • Lau, C. M. L.,Jahanmir G., Chau Y., Local environment-dependent kinetics of ester hydrolysis revealed by direct 1H NMR measurement of degrading hydrogels,  Acta Biomaterialia (101),2020,219-226.
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2019

 
  • ​​Ni R., Chau Y, Nanoassembly of Oligopeptides and DNA Mimics the Sequential Disassembly of a Spherical Virus, Angew. Chem. Int. Ed.2019,58,2–8
  • ​Xu J., Zhao C. Chau  Y., Lee, Y. ,The synergy of chemical immobilization and electrical orientation of T4 bacteriophage on a micro electrochemical sensor for low-level viable bacteria detection via Differential Pulse Voltammetry  , Biosensors and Bioelectronics, 2019
  •  Ni R., Feng R., Chau Y., Synthetic Approaches for Nucleic Acid Delivery: Choose the Right Carriers, Life, 2019, 9(3),59, DOI:10.3390/life9030059
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  • Huang X, Chau Y, Investigating impacts of surface charge on intraocular distribution of intravitreal lipid nanoparticles, Experimental Eye Research, 2019,186,  107711    DOI: 10.1016/j.exer.2019.10771
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  • Chan K. , Yu Y., Ng S., Mak H.,, Yip Y., Merwe Y., Ren T., Yung J., Biswas S., Cao X., Chau Y., Leung C., Intracameral Injection of a Chemically Cross-Linked Hydrogel to Study ChronicNeurodegeneration in Glaucoma, Acta Biomaterialia,2019,94, 219-231   DOI: 10.1016/j.actbio.2019.06.00
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  • Liu J., Ni R. and  Chau Y., Self-assembled Peptidic Nanomillipede to Fabricate Tuneable Hybrid Hydrogel, Chemical Communications, 2019,55,7093-7096  DOI: 10.1039/C9CC02967B 
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  • Huang X, Chau Y, Intravitreal nanoparticles for retinal delivery, Drug Discovery Today, (24) 2019, 1510-1523,  DOI: 10.1016/j.drudis.2019.05.005
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  • ​Feng T.,Huang X., Ni, R., Suen WL, Chau Y. ,  Nanoparticles for drug delivery targeting neurodegeneration in brain and eye, Chapter 6, Nanomaterials for Drug Delivery and Therapy, Andrew William publishers, 2019,149-183
  • Jahanmir G, , Chau Y, Mathematical models of drug release from degradable hydrogels, chapter 9, Biomedical Applications of Nanoparticles, Andrew William publishers, 2019, 233-269
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  • Yu Y, Chau Y.,Long-term therapeutic effect in non-human primate eye from a single injection of anti-VEGF controlled release hydrogel, Bioengineering & Translational Medicine,2019   DOI: 10.1002/btm2.1012
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  • ​Kim M. , Feng T., Zhang Q., Chan H  and  Chau Y. ,Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles, Polymers 2019, 11, 288  DOI:10.3390/polym11020288
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2018

 
  • Xu J, Chau Y, Polymeric nanoparticles decorated with BDNF-derived peptide for neuron-targeted delivery of PTEN inhibitor, European Journal of Pharmaceutical Sciences,2018,124,37-45, DOI: 10.1016/j.ejps.2018.08.020
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  •  Ni R, Liu J,Chau Y., Ultrasound-facilitated assembly and disassembly of pH-sensitive self-assembly peptide, RSC Advances, 2018, 8, 29482 - 29487  DOI: 10.1039/C8RA04391D
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  • Jahanmir G, Abdekhodaie M. J., Chau Y., "​Stochastic Modeling of Degradation Behavior of Hydrogels", Macromolecules, 2018, 51 (11), 3941–3952  DOI: 10.1021/acs.macromol.8b00165
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  • Lau CML, Yu Y, Jahanmir G, Chau Y., "​Controlled release technology for anti-angiogenesis treatment of posterior eye diseases: current status and challenges", Advanced Drug Delivery Reviews,2018,126, 145-161.  DOI:10.1016/j.addr.2018.03.013
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2017

 
  • Ni R and Chau Y. "Tuning the Inter-nanofibril Interaction to Regulate the Morphology and Function of Peptide/DNA Co-assembled Viral Mimics",Angew. Chem, 2017, 56(32), 9356-9360  doi: 10.1002/anie.2017035
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  • Zhou J, Ni R and Chau Y. "​Polymeric vesicle formation via temperature-assisted nanoprecipitation".RSC Adv. , 2017, 7 ,17997-18000 doi : 10.1039/C7RA01959A
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  • Chau Y, Suen WL, Tse HY, Wong HS. "Ultrasound-enhanced penetration through sclera depends on frequency of sonication and size of macromolecules". European Journal of Pharmaceutical Sciences. 2017. Jan 16;100:273-279. doi: 10.1016/j.ejps.2017.01.016.

2016

 
  • Suen WL, Jiang J, Wong HS, Qu J, Chau Y. "Examination of Effects of Low-Frequency Ultrasound on Scleral Permeability and Collagen Network". Ultrasound in Medicine and Biology. 2016. Nov;42(11):2650-2661. doi: 10.1016/j.ultrasmedbio.2016.07.013.
  • Ni R, Zhou J, Hossain N and Chau Y. "Virus-inspired nucleic acid delivery system: Linking virus and viral mimicry". Advanced Drug Delivery Reviews. 2016. 106(Pt A), 3-26. 
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  • Zhou J and Chau Y. "Different oligoarginine modifications alter endocytic pathways and subcellular trafficking of polymeric nanoparticles". Biomaterials Science. 2016. 4, 1462-1472
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2015

 
  • Yu, Y. and Chau, Y. “Injectable chemically crosslinked hydrogel for the controlled release of Bevacizumab in vitreous: a 6-month in vivo study”. Translational Vision Science and Technology. 2015. Mar 10;4(2):5. eCollection 2015

2014

 
  • Ni, R. and Chau, Y. “Structural mimics of viruses through peptide/DNA co‐assembly”. Journal of American Chemical Society. 2014. 136 (52): 17902–17905. (featured in Chemical & Engineering News and Scientific American)
  • Yu, Y. and Chau, Y. “Formulation of In Situ Chemically Cross-linked Hydrogel Depots for Protein Release: From the Blob Model Perspective” Biomacromolecules. 2014. DOI: 10.1021/bm501063n
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  • Chow, D.W.Y., Chau, Y., Yeung, W.K., Westermeyer, H.D. “In vitro evaluation of the inhibitory effect of canine serum, canine fresh frozen plasma, freeze–thaw-cycled plasma, and Solcoseryl™ on matrix metalloproteinases 2 and 9. Article first published online: 18 AUG 2014 | DOI: 10.1111/vop.12204.

  • Suen, W.-L.L., Chau, Y. “Size-dependent internalization of folate-decorated nanoparticles via the pathways of clathrin- and caveolae-mediated endocytosis in ARPE-19 cells” 2014 . Journal of Pharmacy and Pharmacology.  66(4):564-573.​​

2013

 
  • Jiang, L., Wang, W., Chau, Y., Yao, S. “Controllable formation of aromatic nanoparticles in a three-dimensional hydrodynamic flow focusing microfluidic device” RSC Advance, 2013. 3:17762-17769.
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  • Li, Q., Chow, K.L., Chau, Y. “Three-dimensional self-assembling peptide matrix enhances the formation of embryoid bodies and their neuronal differentiation” Journal of Biomedical Materials Research: Part A, 2013. 102(6):1991-2000

  • Suen, W.-L.L., Wong, H.S., Yu,Y., Lau, L.C.M., Lo, A.C.-Y., Chau, Y. “Ultrasound-mediated transscleral delivery of macromolecules to the posterior segment of rabbit eye in vivo” 2013. Investigative Ophthalmology & Visual Science. 54(6):4358-4365.
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  • Suen, W.-L.L., Chau, Y. “Specific uptake of folate-decorated triamcinolone-encapsulating nanoparticles by retinal pigment epithelium cells enhances and prolongs antiangiogenic activity” 2013. Journal of Controlled Release. 167(1):21-28.
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2012

 
  •  Yu, Y. and Chau, Y. “One-step click method for generating vinyl sulfone groups on hydroxyl-containing water soluble polymers” 2012. Biomacromolecules. (3): 937–942 (Most read article in Q1 2012)
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  • Wang, W. and Chau, Y. “Self-Assembly Mediated Platform for Rapid and Facile Preparation of Peptide-Functionalized Nanoparticles with High Stability” 2012. Chemistry of Materials. (5): 946–953
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  • Li, Q., Cheung, W.H., Chow, K.L., Ellis-Behnke, R.G., Chau, Y. “Factorial analysis of adaptable properties of self-assembling peptide matrix on cellular proliferation and neuronal differentiation of pluripotent embryonic carcinoma” 2012. Nanomedicine: Nanotechnology, Biology and Medicine. 8(5):748-56
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2011

 
  • Wang, W. and Chau, Y. “Efficient and facile formation of two-component nanoparticles via aromatic moiety directed self-assembly” 2011. Chemical Communications 47(37): 10224 – 10226. (Cover article)
  • Li, Z. and Chau, Y. “A facile synthesis of branched poly(ethylene glycol) and its heterobifunctional derivatives” 2011. Polymer Chemistry. 2:873-878.

  • Li, Z. and Chau, Y. “Synthesis of X(Y)-(EO)n-OCH3 type heterobifunctional and X(Y)-(EO)n-Z type heterotrifunctional poly(ethylene glycol)s” 2011. Bioconjugate Chemistry. 22: 518-522

2010

 
  • Zhong, J. and Chau, Y. “Synthesis, characterization, and thermodynamic study of a polyvalent lytic peptide-polymer conjugate as novel anticancer agent” 2010. Bioconjugate Chemistry 21:2055-2064.

  • Li, Z. and Chau, Y.  “Synthesis of heterobifucntional polyethylene glycol by an acetal protection method”, 2010. Polymer Chemistry 1 (10):1559-1601.
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  • Zhou, P., Li, Z., Chau, Y. “Synthesis, characterization, and in vivo evaluation of poly(ethylene oxide-co-glycidol)-platinate conjugate” 2010. European Journal of Pharmaceutical Sciences 41:464-472.
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  • Cheung, A.C.Y., Yu, Y., Tay, D., Wong, H.S., Ellis-Behnke, R., Chau, Y. “Ultrasound-enhanced intrascleral delivery of protein” 2010. International Journal of Pharmaceutics 401: 16-24.

  • Li, Q. and Chau, Y. “Neural differentiation directed by self-assembling peptide scaffolds presenting laminin-derived epitopes”, 2010. Journal of Biomedical Materials Research. Part A 94(3):688-99.

  • Ko, E.I., Chau, Y. “Integrating Academic and Mentoring Support for the Development of First-year Chemical Engineering Students in Hong Kong” 2010. Chemical Engineering Education 44(1):44-64.

2009

 
  • ​​​ Wang, W. and Chau, Y. “Self-assembled peptide nanorods as building blocks of fractal patterns” 2009. Soft Matter 5(24): 4893-4898. (Cover article and featured in Highlights in Chemical Science).
  • Li, Z. and Chau, Y. “Synthesis of linear polyether polyol derivatives as new materials for bioconjugation” 2009. Bioconjugate Chemistry 20(4):780-789.  (Most read article in the month of April 2009)

2008

 
  •  Zhong, J. and Chau, Y. "Anti-tumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase" 2008. Molecular Cancer Therapeutics 7(9):2933-40.
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  • Wang, W., Yang, Z., Patanavanich, S., Xu, B., Chau, Y. "Controlling self-assembly within nanospace for peptide nanoparticle fabrication” 2008. Soft Matter 4 (8): 1617 – 1620.
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  •  Chau, Y., Luo, Y., Cheung, A.C.Y., Nagai, Y., Zhang, S., Kobler, J., Zeitels, S.M. and Langer, R.  “Incorporation of a Matrix Metalloproteinase-Sensitive Substrate into Self-Assembling Peptides – A Model for Biofunctional Scaffolds” 2008. Biomaterials 29(11):1713-9.

2006

 
  • Chau, Y., Dang, N.M., Tan, F.E., Langer, R. “Investigation of targeting mechanism of new dextran-peptide-methotrexate conjugates using biodistribution study in matrix-metalloproteinase overexpressing tumor xenograft model ” 2006. Journal of Pharmaceutical Sciences 95: 541-51.
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2005

 
  • Chau, Y., Padera, R.F., Dang, N.M., Langer, R. “Antitumor efficacy of a novel polymer peptide drug conjugate in human tumor xenograft models” 2005. International Journal of Cancer 118: 1519-26.

before 2005

 
  • Chau, Y., Tan, F.E., Langer, R.“Synthesis and characterization of dextran-peptide-methotrexate conjugates for tumor targeting via mediation by matrix-metalloproteinase II and matrix-metalloproteinase IX” 2004. Bioconjugate Chemistry 15(4):931-941.

  • Kohane, D.S., Holmes, G.L., Chau, Y., Zurakowski, D., Langer, R., Cha, B.H. “Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures” 2002. Epilepsia 43: 1462-1468.
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  • Bothwell, M.K., Daughetee, S.D., Chau,Y., Wilson, D.B. and Walker L.P. “Binding capacities of Thermomonospora fusca E3,E4 and E5, the E3 binding domain, and Trichoderma ressei CBHI on Avicel and bacterial microcrystalline cellulose” 1997. Bioresources Technology 60:169-178.
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